GATA6 is a crucial regulator of Shh in the limb bud.
In the limb bud, patterning along the anterior-posterior (A-P) axis is controlled by Sonic Hedgehog (Shh), a signaling molecule secreted by the "Zone of Polarizing Activity", an organizer tissue located in the posterior margin of the limb bud.We have found COCONUT OIL ORG VIR that the transcription factors GATA4 and GATA6, which are key regulators